Which Is Actually Cheaper for Everyday Items: CVS or Amazon?
Many Americans shop at both CVS and Amazon for everyday essentials, but few realize how their pricing strategies differ. CVS markets itself as the convenient neighborhood option where you can grab shampoo while picking up prescriptions. Amazon built its reputation on competitive pricing and vast selection delivered to your door.

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Yet, they have a complex pricing ecosystem that can make identical products cost twice as much at one retailer compared to another. The gap has grown so significant that some shoppers now treat drugstore chains like overpriced convenience stores, while others have discovered ways to game CVS’s coupon system for better deals than Amazon offers.
Understanding which retailer actually saves you money requires looking beyond sticker prices to examine membership costs, shipping fees, product authenticity, and the hidden time investment required to access the best deals.
The Markup Reality Check
A comprehensive 2024 study by Profitero analyzed 14,000 items across major U.S. retailers and found that Amazon’s prices averaged 14% lower than those of its competitors.
CVS stood out for all the wrong reasons. Health and personal care items cost significantly more than Amazon’s prices, and real shoppers regularly discover even starker differences. One Reddit user found identical items jumping from $10 on Amazon to $25.99 at CVS. That’s a 160% markup. Another product leaped from $13.99 to $30.99, representing a 121% price increase for the exact same item.
These aren’t isolated incidents. A separate price comparison of household essentials found CVS consistently ranked among the most expensive options.
The Coupon Ecosystem Changes Everything

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Many personal accounts suggest that CVS operates what amounts to a pricing shell game, which inflates base prices to fund an elaborate discount system. Regular app users receive 40% off coupons, manufacturer coupon stacking opportunities, and ExtraCare rewards that can slash total costs dramatically.
Savvy customers report buying three boxes of cereal for $1.98 through strategic coupon combining—a 90% discount that beats any Amazon deal. Others stack multiple offers to get brand-name items essentially free. The catch is that this requires time, planning, and shopping around CVS’s promotional calendar rather than your actual needs.
Customer sentiment suggests this system works for dedicated users but frustrates casual shoppers who pay full freight. Even with significant discounts applied, some items remain more expensive than Amazon’s regular prices, which leads to the uncomfortable realization that “40% off” still means overpaying.
Amazon’s Hidden Costs
Amazon’s rock-bottom prices come with their own complications. Counterfeit products flood categories like skincare, vitamins, and medications. You might save $7 on face wash only to discover months later that you’ve been using fake ingredients with unknown effects.
The problem affects everything from basic toiletries to over-the-counter medications. Experienced Amazon shoppers develop strategies to avoid obvious fakes, but the risk never disappears completely. CVS might charge more, but product authenticity is guaranteed.
Amazon also requires planning ahead for most purchases. Their two-day Prime shipping won’t work when you’re sick at 2 AM and need cold medicine immediately. CVS capitalizes on these urgent moments when price becomes secondary to availability.
The Strategic Shopping Approach

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Smart shoppers use both retailers strategically rather than choosing sides. Amazon works best for planned purchases, bulk buying, and price-sensitive items where authenticity concerns are minimal. CVS makes sense for immediate needs, prescription coordination, and situations where their coupon system creates genuine savings.
The worst approach involves paying CVS’s full prices without engaging its discount ecosystem. That’s where you encounter the full convenience premium, sometimes 200-300% markups.
Amazon wins on pure price comparison for most identical items. However, CVS’s coupon system can flip this equation for engaged customers willing to work their promotional mechanics.